?2M in the Horseshoe Crab A Structural and Functional Invertebrate Homologue

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A homologue of alpha 2-macroglobulin purified from the hemolymph of the horseshoe crab Limulus polyphemus.

A high molecular weight protease inhibitor has been purified from the cell-free plasma of the horseshoe crab Limulus polyphemus using high speed centrifugation, polyethylene glycol precipitation, and gel filtration. The inhibitor is sensitive to mild acidification, methylamine treatment, and inhibits the proteolytic activity of a variety of endopeptidases. The molecule does not inhibit trypsin-...

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Protecting Horseshoe Crab Habitat

Each spring adult horseshoe crabs migrate from deep bay waters and the Atlantic continental shelf to intertidal sandy beaches to spawn. Horseshoe crabs are an important food source for migrating shorebirds that feed on the eggs, for migrating fish that feed on the eggs and larvae and for Atlantic loggerhead turtles that feed on horseshoe crabs while using the Chesapeake Bay as a summer nursery ...

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Hemocyanin of the Horseshoe Crab, Limzdus polyphemus

The high molecular weight hemocyanin found in the hemolymph of the horseshoe crab, Limulus polyphemus, is composed of at least eight different kinds of subunits. Ion exchange chromatography at high pH in the presence of EDTA yields five major zones, hemocyanins I to V, three of which are electrophoretically heterogeneous. The subunits have similar molecular weights, 65,000 to 70,000, and their ...

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Companions at a Distance: Technoscience, Blood, and the Horseshoe Crab

In this paper we present a particular history of Limulus polyphemus, the horseshoe crab, as a means of expanding on Haraway’s notion of companion species. Drawing on accounts of the horseshoe crab’s role, on the one hand, in work of the Serological Museum at Rutgers University that spanned the 1940s to the 1970s, and, on the other, in the development of the limulus amebocyte lysate test, we tra...

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ژورنال

عنوان ژورنال: Annals of the New York Academy of Sciences

سال: 1994

ISSN: 0077-8923,1749-6632

DOI: 10.1111/j.1749-6632.1994.tb44312.x